The Auspitz sign—pinpoint bleeding when outer scales are removed from psoriatic plaques—is a classic finding in psoriasis, along with several more or less. Synonyms: Auspitz sign, “Phänomen des blutigen Taus” (“phenomenon of bloody dew”). Definition of the phenomenon: The Auspitz phenomenon is the. This page includes the following topics and synonyms: Auspitz Sign.
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Psoriasis is a common chronic inflammatory skin disorder affecting individuals with an underlying genetic predisposition. The disease manifests following exposure to various triggers e. The typical lesions are sharply demarcated, erythematousscaly, pruritic plaqueswhich occur most often on the extensor surfaces of the knees and elbowsbut may also affect the scalp and back.
Other common clinical findings include involvement of the nails e. As psoriasis presents with several subtypes, the size, location, and severity of the lesions vary. The diagnosis is based primarily on clinical findings, but may also be confirmed with tests e. Mild psoriasis is treated with topical agents such as steroids, whereas moderate to severe disease requires systemic therapy e. Epidemiological data refers to the US, unless otherwise specified. If first-degree relatives of patients with psoriasis have joint problems, psoriatic arthritis should be considered!
Psoriasis – Knowledge for medical students and physicians
Ultraviolet light is effective in treating dermatological conditions, as it has antiproliferative effects slowing keratinization and anti-inflammatory effects inducing apoptosis of pathogenic T cells on the skin. We list the most important complications. The selection is not exhaustive. Clinical science Psoriasis is a common chronic inflammatory skin disorder affecting individuals with an underlying genetic predisposition.
Increased proliferatio n of keratinocytes Acanthosis: The mechanism causing the immune response is not yet well understood. Cutaneous variants Plaque psoriasis: Physical stimuli or skin injury e.
Epidermal infiltration by lymphocytes is common. Chronic fluid accumulation leads to the formation of intraepidermal vesicles.
Laboratory tests In case of psoriatic arthritis: Differential diagnosis of scaling Lesion Distribution Psoriasis Clearly demarcatederythematous plaques with silvery scalingpruritus Scalp Extensor surfaces of joints kneeselbows Back Atopic dermatitis Poorly demarcatedeczemawhite scales, severe xerosis and pruritus Extensor surfaces of extremities e.
Medical therapy Mild to moderate psoriasis Moderate to severe psoriasis Severe psoriasis First-line: Topical treatment Adverse effects Topical steroids Skin atrophy with chronic use Risk: Increased risk of other comorbidities Metabolic syndrome Cardiovascular diseases hypertensioncoronary heart diseasemyocardial infarctionstroke Chronic kidney disease References: Lifelong diseaseusually benign Patients may experience remissions of varying lengths; acute episodes of exacerbation possible.
Psoriasis is associated with depression and a decreased quality of life.
Clearly demarcatederythematous plaques with silvery scalingpruritus. Scalp Extensor surfaces of joints kneeselbows Back.
Auspitz’s sign – Wikipedia
Poorly demarcatedeczemawhite scales, severe xerosis and pruritus. Extensor surfaces of extremities e. Clearly demarcated, erythematous plaquesgreasy-looking yellow scales. Disseminated, plaques with orange-pink scaleshyperkeratosiserythroderma. Typically palms and soles Islands of unaffected skin sparing Follicular keratosis. Erythemascaling 2—6 days following onset, auuspitz of underlying diseasepruritus.
Generalized erythema Scaling initially in flexural creases. Topical medication as combination therapy Add systemic agents as needed methotrexateretinoidcyclosporine Phototherapy.
Skin atrophy with chronic use Risk: Long term use Increased risk of skin cancer Premature aging of the skin. Liver and lung toxicity. Etanerceptadalimumabinfliximab.